Pachers masterpiece, the St. Wolfgang Altarpiece (1471–1481), is considered one of the most remarkable carved and painted altar shrines in all of European art. It contains scenes from the life of Jesus and the Virgin Mary. Pachers other great work, the Altarpiece of the Church Fathers, created in 1483 for Neustift Monastery, combined painting and sculpture to produce a unique art form.
Pachers influence was primarily North Italian, and his work shares characteristics with that of painters such as Andrea Mantegna. German influences, however, are also evident in his work, especially in his wood sculpture. Pachers fusion of Italian Renaissance and Northern Gothic realism helped him to produce a uniquely personal style of painting.